OMICS OF asnA GENE FROM Enterobactor aerogenes KCTC2190
DOI:
https://doi.org/10.59415/ijfas.v2i2.45Keywords:
asnA gene, Enterobactor aerogenes,Anticancer, Asparginase, Primary & Secondary structure, Glycosylation.Abstract
Background & Aim: The present study was carried out to evaluate the omics of asnA gene from
Enterobactor aerogenes strain KCTC2190. Methods: This was achieved by using various online
computational tools for both genomic and proteomic analysis. Results: Genomic studies states that the
pyramidine rich gene codes for 388 aminoacid peptide with approximately 37KD (ss DNA) containing
both left & right primers, a hybridization probe and several restriction sites for restriction enzymes. The
corresponding peptide primary structure reveals that it is an acidic, stable protein. Secondary structure
defines that it mainly contains the random coils & alpha helix. The protein has a total of ten
phosphorylation sites along with net N & O-Glycosylation sites. Conclusion: The present study states
that the pyramidine rich gene has both left & right primers, Hybridization probe with sufficient GC
content. The encoded acidic, stable peptide ahs the multiple sites for phosphorylation, glycosylation.
Above results shows that the asnA from Enterobactor aerogenes strain KCTC2190 is much suitable for
the experiments to enhance the L-Asparginase enzyme.
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