Scrutinizing the antioxidant potential of Prunella vulgaris L. : A medicinal plant from central Himalayan region

Authors

  • Tapan Kumar Nailwal
  • Manoj Kumar Singh
  • Charu Joshi
  • Neelu Joshi
  • Ruchika Sharma
  • Latika Brijwal
  • Ravi Shekhar Kumar

DOI:

https://doi.org/10.59415/ijfas.v4i1.65

Keywords:

Prunella vulgaris; antioxidants; Phenol; Flavonoid; DPPH; ABTS; metal chelating

Abstract

Background & Aim: The present study was carried out to evaluate the in vitro antioxidant activities of methanolic extract of
Prunella vulgaris, a valuable medicinal plant from Central Himalayans. Methods: This was achieved by screening of the plant
extracts at varying concentrations (1-70 μ g/ml), using 2,2-diphenyl-1-picryl- hydrazyl (DPPH) radical scavenging activity,
reducing power assay superoxide radical scavenging activity, metal chelating activity, and analysis of total antioxidant activity by
ABTS method. Results: Total phenol and flavonoid contents (17.200±0.306 mg gallic acid equivalent (GAE)/g dry weight and
3.920±0.042 mg quercetin equivalents (QE)/g dry weight) were found respectively. Scavenging effect of methanolic extracts of P.
vulgaris was four times greater than that of the synthetic antioxidant ascorbic acid. Conclusion: Results also suggests a close
relationship between total phenolic content and antioxidant activity, reducing power and radical scavenging effect on DPPH
radicals, which proves P. vulgaris is a potential source of useful natural antioxidants.

Author Biographies

  • Tapan Kumar Nailwal

    Department of Biotechnology, Bhimtal Campus, Kumaun University,
    Nainital-263136, Uttarakhand, India
    Phone no. +919412986483
    E-mail: tapannailwal@gmail.com

  • Manoj Kumar Singh

    Department of Biotechnology, Bhimtal Campus, Kumaun University,
    Nainital-263136, Uttarakhand, India

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Published

2015-03-30

Issue

Vol. 4 No. 1 (2015): International Journal of Fundamental and Applied Sciences

Section

Articles

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How to Cite

Scrutinizing the antioxidant potential of Prunella vulgaris L. : A medicinal plant from central Himalayan region. (2015). International Journal of Fundamental and Applied Sciences (IJFAS), 4(1), 1-8. https://doi.org/10.59415/ijfas.v4i1.65